Ascoli was founded by an Italic population (Piceni) several centuries before Rome's founding on the important Via Salaria, the salt road that connected Latium with the salt production areas on the Adriatic coast. In 268 BC it became a civitas foederata, a "federated" city with nominal independence from Rome. In 91 BC, together with other cities in central Italy, it revolted against Rome, but in 89 BC was reconquered and destroyed by Pompeius Strabo. Its inhabitants acquired Roman citizenship, following the developments and the eventual fall of the Roman Empire.